Programme
| Sunday, December 3, 2017 | |
|---|---|
| 16:00-17:00 | Registration |
| 17:00-17:15 | Opening Remarks: |
| 17:15-18:00 | Plenary Lecture 1: Glucagon-related peptides and GIP, a 2017 update |
| 18:00-20:00 | Cocktail Reception |
| 20:00 | Coach departs for the peak |
| 20:00-22:30 | Visit to the Victoria Peak |
| Monday, December 4, 2017 | |
| 08:00-08:30 | Registration |
| 08:30-09:15 | Akira Arimura Young Investigator Award Lecture: PACAP and VIP regulation of the immune system and therapeutic perspectives |
| 9:15-10:15 | Oral Communication 1Chair: Dr. Andrea Tamás, University of Pécs, HungaryDr. Rongjie Yu The allosteric site in the N-terminal extracellular domain of class B GPCR PAC1 Mr. Sai Wun On The relationship between the evolutionary origin of PACAP/GCG subfamily and two rounds of whole genome duplication (2WGD) in the beginning of vertebrate evolution Dr. Jozsef Kun Hemokinin-1 activates cultured trigeminal neurons and its TAC4 mRNA is upregulated in a rat orofacial pain model Dr. Aung Moe Zaw Secretin deficiency causes cardiopulmonary pathologies in mice |
| 10:15-10:45 | Tea break/Poster |
| 10:45-12:25 | Symposium 1: PACAP and nociception processing |
| 10:45-11:10 | PACAP and the memory of pain: learning and forgetting Prof. James Waschek, University of California Los Angeles, USA |
| 11:10-11:35 | Involvement of spinal Cyr61/CCN1 in PACAP-specific receptor-induced long-term mechanical allodynia in mice Dr. Takashi Kurihara, Kagoshima University, Japan |
| 11:35-12:00 | Development of small-molecule Pac1 receptor antagonists aimed at drug discovery of novel analgesics. Dr. Ichiro Takasaki, Toyama University, Japan |
| 12:00-12:25 | Parabrachial PACAP and emotional component of pain Prof. Victor May, University of Vermont, USA |
| 12:25-12:35 | Conference group Photo |
| 12:35-14:00 | Lunch Break/Poster Presentation |
| 14:00-15:40 | Symposium 2: PACAP and neuroprotection |
| 14:00-14:25 | Protective and antioxydative effects of PACAP in a fetal alcohol syndrome model Dr. Olfa Masmoudi, University Tunis El Manar, Tunis |
| 14:25-14:50 | PACAP receptor expression in parkinsonian monkey brain Prof. Dora Reglodi, University of Pecs, Hungary |
| 14:50-15:15 | PACAP-producing human adipose-derived stem cells and their therapeutic use in a murine stroke model Ms. Gruel R, Rouen University, France |
| 15:15-15:40 | Gut microbiota changes in PACAP deficient mice - bifidobacteria make the difference Dr. Markus M. Heimesaat, Charité - Universitätsmedizin Berlin, Germany |
| 15:40-16:00 | Tea break/Poster |
| 16:00-18:15 | Symposium 3: New Horizons in VIP, PACAP and Secretin: Research towards Innovative Clinical Applications |
| 16:00-16:25 | PACAP enhances learning and memory and protects against stress in the Adnp-deficient mouse model of the autism-related ADNP syndrome Prof. Illana Gozes, Tel Aviv University, Israel |
| 16:25-16:50 | CDK2 inhibition by PACAP/AC/PKA signaling: A novel drug target Dr. Diana Piol, University of Trento, Italy |
| 16:50-17:15 | Pre-clinical evaluation of VIP-Elastin-Like-Polypeptides PB1046 & PB1120 for the treatment of Cystic Fibrosis Dr. Valerie Chappe, Dalhousie University, Canada |
| 17:15-17:35 | Expression and functional implications of secretin in cerebellar cortex Dr. Li Zhang, Jinan University, China |
| 17:35-17:55 | PACAP promotes sweat secretion in eccrine gland via PAC1R Dr. Jun Watanabe, Showa University, Japan |
| 17:55-18:15 | Examination of pituitary adenylate cyclase activating polypeptide (PACAP) as a potential biomarker in heart failure patients Dr. Andrea Tamás, University of Pécs, Hungary |
| 19:00-21:00 | Council Meeting |
| Tuesday, December 5, 2017 | |
| 08:30-09:15 | Plenary Lecture 2: Optical functionalization of human Class A orphan G-protein coupled receptors |
| 09:15-10:15 | Oral communication 2Chair: Dr. Leo T.O. Lee, University of MacauMs. Oi Kwan Mak Central role of SCTR-AT1aR heterocomplex in modulating Vasopressin release and expression within hypothalamus Dr. Adel Jungling The effects of Postnatal enriched environment and PACAP in aging rat model of Parkinson’s disease Dr. Balazs Opper Investigation of possible functions of PACAP in human small intestinal epithelial cells Ms. Christina Van Role of PACAP/PAC1 in protecting neurons and modulating inflammation in a model of multiple sclerosis and optic neuritis |
| 10:15-10:45 | Tea break/Poster |
| 10:45-12:25 | Symposium 4: GPCR ensembles to platforms: mechanisms and insights to PACAP receptor signaling |
| 10:45-11:10 | PACAP receptors: an ensemble in play Prof. Victor May, University of Vermont, USA |
| 11:10-11:35 | Signaling to effect: the role of NCS-Rapgef2 in ERK activation initiated by PAC1 and other Gs-coupled GPCRs Prof. Lee Eiden, NIH/NIMH, USA |
| 11:35-12:00 | Spinal astrocyte-neuron lactate shuttle contributes to PAC1-induced long-term mechanical allodynia Prof. Yuki Kambe, Kagoshima University, Japan |
| 12:00-12:25 | Src family kinases contribute to PACAP-induced PAC1 internalization, generation of phosphorylated ERK and enhancement of neuronal excitability Prof. Rodney Parsons, University of Vermont, USA |
| 12:25-14:00 | Lunch Break/Poster Presentation |
| 14:00-15:40 | Symposium 5: Basic and Translational Research of PACAP/VIP related peptides in Brain and Peripheral Organs |
| 14:00-14:25 | Basic and translational approach to neurodegenerative injuries Prof. Seiji Shioda, Hoshi University, Japan |
| 14:25-14:50 | Peptide protection against autophagy is coupled to behavioral improvements in schizophrenia Prof. Illana Gozes, Tel Aviv University, Israel |
| 14:50-15:15 | Characterization of PACAP neuroprotective effects and approaches for therapeutic applications Dr. David Vaudry, Rouen University, France |
| 15:15-15:40 | PACAP protects dry eye and dry mouth via AQP5 signaling pathway Dr. Tomoya Nakamachi, Toyama University, Japan |
| 15:40-16:00 | Tea break/Poster |
| 16:00-17:40 | Symposium 6: Orally Active VIP Agonists and Their Roles in The Management of Cardiovascular, Renal, Lung and Liver Diseases |
| 16:00-16:25 | VIP and VB0004 in systolic hypertension, cardiac and renal fibrosis Dr. Karen Duggan, Vectus Biosystems, Australia |
| 16:25-16:50 | VIP as Therapeutic Agent for Idiopathic Pulmonary Fibrosis, COPD and Bladder Cancer Mr. Po Hsuan Huang, Stony Brook University, USA |
| 16:50-17:15 | Pacap in the bed nucleus of the stria terminalis mediates stress-induced reinstatement of cocaine seeking in rats Ms.Olivia W. Miles, University of Vermont, USA |
| 17:15-17:40 | VPAC platform in theranostic oncology Prof. Mathew L. Thakur, Thomas Jefferson University, USA |
| 18:30 | Coach departs for Aberdeen ferry Pier |
| 19:00-23:00 | Congress Dinner: Jumbo Kingdom floating restuarant, Aberdeen |
| Wednesday, December 6, 2017 | |
| 09:00-10:00 | Oral communication 3Chair: Dr. Harald Janovjak, Institute of Science and Technology AustriaMs. Lei Wang A role of secretin in postnatal development of Purkinje cells Dr. Balazs Sandor Possible connection of Notch and PACAP signalling in teeth of PACAP-Deficient mice Ms. Payrits Maja Estradiol sensitizes the transient receptor potential vanilloid 1 receptor in pain responses Dr. Balazs D. Fulop Examination of hearing impairment in PACAP-deficient mice |
| 10:00-10:30 | Tea break |
| 10:30-13:00 | Symposium 7: PACAP, VIP and Related Peptides: Master regulators of metabolism |
| 10:30-10:55 | PACAP's role in the regulation of energy expenditure Dr. Sarah Gray, University of Northern British Columbia, Canada |
| 10:55-11:20 | Astrocyte-neuron lactate shuttle plays pivotal role in PACAP mediated fear memory acquisition or retrieval in mice Ms. Yu Nakashima, Kagoshima University, Japan |
| 11:20-11:45 | Secretin and Lipid Metabolism Dr. Revathi Sekar, The University of Hong Kong, Hong Kong |
| 11:45-12:10 | Role of VIP in Adipogenesis Prof. Joseph Pisegna, University of California at Los Angeles, VA Medical Center, USA |
| 12:10-12:35 | Distinct populations of ARC NPY neurons control different aspects of energy homeostasis Prof. Herbert Herzog, Garvan Institute of Medical Research, Australia |
| 12:35-13:00 | Revisiting the Glucose-dependent Insulinotropic Polypeptide (GIP) receptor as a drug target for metabolic diseases Prof. Mette Rosenkilde, University of Copenhagen, Denmark |
| 13:00-13:10 | Closing remarks |
| 13:10-14:30 | Lunch Break |
| 14:30 | Coach departs for Central ferry pier |
| 15:00-15:45 | Ferry to Lamma Island (drop of points Mo Tat Wan or Sok Kwu Wan) |
| 16:00-18:30 | Hike in Lamma Island, from Mo Tat Wan to Sok Kwu Wan(optional) |
| 18:30-21:30 | Dinner |
| 22:00 | Ferry departs to Central ferry pier |